Effect of Ursodeoxycholic Acid Alone and Ursodeoxycholic Acid Plus Domperidone on Radiolucent Gallstones and Gallbladder Contractility in Humans

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Effect of Ursodeoxycholic Acid Alone and Ursodeoxycholic Acid Plus Domperidone on Radiolucent Gallstones and Gallbladder Contractility in Humans

Background/Aims. The aim of this study was to compare the effects of ursodeoxycholic acid (UDCA) alone and UDCA plus domperidone on dissolution of solitary or multiple gallstones. Methods. Fifty-three patients with cholesterol gallstones were randomized into three treatment groups: group I (n = 22) was given UDCA (15 mg/kg/day) alone and group II (n = 18) was treated with domperidone (30 mg/day...

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Calcification of radiolucent gall stones during treatment with ursodeoxycholic acid.

645 Physiologically the electroencephalographic changes comprised pronounced reduction in fast-wave activity as the drugs were withdrawn. This drug-related effect is the reverse of the increase normally seen after administration of benzodiazepines.1 We have also observed that auditory-evoked responses to clicks increase from very small prewithdrawal values to normal values over the same time. T...

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Ursodeoxycholic acid

Ursodeoxycholic acid is an epimer of chenodeoxycholic acid (DB06777). It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic. [PubChem] Indication: The drug reduces cholesterol absorption and is used to dis...

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Ursodeoxycholic acid dissolution of gallstones in cystic fibrosis.

The dissolution of cholesterol gall stones is documented in two adults with cystic fibrosis. Improved care of patients with cystic fibrosis has meant that most survive into adult life. Consequently extrathoracic complications are assuming greater importance, especially those of the hepatobiliary system. These include progressive biliary cirrhosis (25%) leading to portal hypertension and oesopha...

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ژورنال

عنوان ژورنال: Gastroenterology Research and Practice

سال: 2012

ISSN: 1687-6121,1687-630X

DOI: 10.1155/2012/159438